LAMP2A regulates the loading of proteins into exosomes.
João Vasco Ferreira, José Ramalho, Catarina Máximo Carvalho, Maria Helena Cardoso, Petra Pintado, Ana Sofia Carvalho, Hans Christian Beck, Rune Matthiesen, Mónica Zuzarte, Henrique Girão, Guillaume van Niel, Paulo Pereira. bioRxiv, (2021). https://doi.org/10.1101/2021.07.26.453637 (Preprint)
Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis.
Ferreira JV, Rosa Soares A, Ramalho JS, Ribeiro-Rodrigues T, Máximo C, Zuzarte M, Girão H, Pereira P.PLoS One. 2019 Oct 15;14(10):e0223790. doi: 10.1371/journal.pone.0223790. eCollection 2019.PMID: 31613922 Free PMC article. (IF: 3.240, 7 citations)
K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy.
Ferreira JV, Soares AR, Ramalho JS, Pereira P, Girao H.Sci Rep. 2015 May 11;5:10210. doi: 10.1038/srep10210.PMID: 25958982 Free PMC article. (IF: 5.228, 77 citations)
Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells.
Soares AR, Martins-Marques T, Ribeiro-Rodrigues T, Ferreira JV, Catarino S, Pinho MJ, Zuzarte M, Isabel Anjo S, Manadas B, P G Sluijter J, Pereira P, Girao H.Sci Rep. 2015 Aug 19;5:13243. doi: 10.1038/srep13243.PMID: 26285688 Free PMC article. (IF: 5.228, 120 citations)
AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions.
Ribeiro-Rodrigues TM, Catarino S, Marques C, Ferreira JV, Martins-Marques T, Pereira P, Girão H.FASEB J. 2014 Nov;28(11):4629-41. doi: 10.1096/fj.13-248963. Epub 2014 Jul 28.PMID: 25070368 (IF: 5.043, 35 citations)
STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy.
Ferreira JV, Fôfo H, Bejarano E, Bento CF, Ramalho JS, Girão H, Pereira P.Autophagy. 2013 Sep;9(9):1349-66. doi: 10.4161/auto.25190. Epub 2013 Jun 7.PMID: 23880665 (IF:16.016, 127 citations)