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CHRC, CEDOC, Pólo de Investigação, NMS, UNL. Edifício Amarelo Rua do Instituto Bacteriológico, nº5, 1150-082 Lisboa, Portugal
Telefone: 218803105

Saba Abdulghani Oliveira da Silva

Investigador Investigador Doutorado
Senior Researcher, Coordinator of CHAIN Biobank

Saba Abdulghani is the coordinator of the Comprehensive Health biobank (CHAIN) at the Comprehensive Health Research Centre, Nova Medical School and a researcher at CEDOC, NMS. She holds a doctorate degree in Biomaterials from Queen Mary University of London, UK. Following her PhD, Saba was awarded a Marie Curie Fellowship to work at the Orthopaedics department at Lund University Hospital in Sweden.

She later moved to Portugal to join the Rheumatology research unit at Instituto de Medicina Molecular (IMM) and work on the nanomechanical properties of osteoporotic bone where she was awarded the European Calcified tissue Society fellowship. Her main area of research is the nanostructure of osteoporotic bone in early and post-menopausal women and biobanking.

  1. Lopes DG, Henriques AR, Santos-Dias M, Nunes-da-Silva C, Gonçalves J, de Sousa RD, Abdulghani S, Eletério J, Braga SJ, Soares H, Branco JC, Canhão H, Rodrigues AM. Staff SARS-CoV-2 Seroprevalence and Mental Health as Key Factors in University Response to COVID-19 Pandemic. Front Public Health. 2021 Jun 16;9:689919. doi: 10.3389/fpubh.2021.689919.
  2. Abdulghani S, Mitchell GR. Biomaterials for In Situ Tissue Regeneration: A Review. Biomolecules. 2019 Nov 19;9(11):750. doi: 10.3390/biom9110750.
  3. Abdulghani S, Morouço PG. Biofabrication for osteochondral tissue regeneration: bioink printability requirements. J Mater Sci Mater Med. 2019 Jan 28;30(2):20. doi: 10.1007/s10856-019-6218-x.
  4. Vidal B, Pinto A, Galvão MJ, Santos AR, Rodrigues A, Cascão R, Abdulghani S, Caetano-Lopes J, Ferreira A, Fonseca JE, Canhao H. Bone histomorphometry revisited. Acta Reumatol Port. 37(4):294-300, 2012. PMID: 24126421
  5. Caetano-Lopes J, Nery AM, Canhão H, Duarte J, Cascão R, Rodrigues A, Perpétuo IP, Abdulghani S, Amaral PM, Sakaguchi S, Konttinen YT, Graça L, Vaz MF, Fonseca JE.Chronic arthritis leads to disturbances in the bone collagen network. Arthritis Res Ther. 2010;12(1):R9. doi: 10.1186/ar2908. Epub 2010 Jan 15.
  6. J Caetano-Lopes 1, A M Nery, R Henriques, H Canhão, J Duarte, P M Amaral, M Vale, R A Moura, P A Pereira, P Weinmann, S Abdulghani, M Souto-Carneiro, P Rego, J Monteiro, S Sakagushi, M V Queiroz, Y T Konttinen, L Graça, M F Vaz, J E Fonseca. Chronic arthritis directly induces quantitative and qualitative bone disturbances leading to compromised biomechanical properties. Clin Exp Rheumatol. May-Jun 2009;27(3):475-82.
  7. Abdulghani, S.; Caetano-Lopes, J.; Canhão, H.; Fonseca, J.E. Biomechanical effects of inflammatory diseases on bone-rheumatoid arthritis as a paradigm. Autoimmunity Reviews, Volume 8, Issue 8, July 2009, Pages 668-671. doi: 10.1016/j.autrev.2009.02.021
  8. Ørskov M, Abdulghani S, McCarthy I, Søballe K, Flivik G.Comparison of flanged and unflanged acetabular cup design. An experimental study using ceramic and cadaveric acetabuli. Acta Orthop. 2010 Oct;81(5):556-62. doi: 10.3109/17453674.2010.519167. 
  9. Kjellson F, Abdulghani S, Tanner KE, McCarthy ID, Lidgren L.Effect of iodixanol particle size on the mechanical properties of a PMMA based bone cement. J Mater Sci Mater Med. 2007 Jun;18(6):1043-51. doi: 10.1007/s10856-006-0116-8. Epub 2007 Jan 30. 
  10. Xu H, Abdulghani S, Behiri J, Sabokbar A.Osteolytic potential of triphenyl bismuth as an alternative contrast medium in acrylic bone cement. J Biomed Mater Res B Appl Biomater. 2005 Oct;75(1):64-73. doi: 10.1002/jbm.b.30277.
  11. Abdulghani S, Wang JS, McCarthy I, Flivik G.The influence of initial pressurization and cup introduction time on the depth of cement penetration in an acetabular model. Acta Orthop. 2007 Jun;78(3):333-9. doi: 10.1080/17453670710013889.
  12. Sheng Wang J, Tanner KE, Abdulghani S, Lidgren L. Indentation Testing of a Bone Defect Filled with Two Different Injectable Bone Substitutes. Key Engineering Materials (Volumes 284-286): 89-92, 2005. doi.org/10.4028/www.scientific.net/KEM.284-286.89 
  13. Abdulghani S, Nazhat SN, Behiri JC and Deb S. Effect of triphenyl bismuth on glass transition temperature and residual monomer content of acrylic bone cements. Journal of Biomaterials Science, Polymer Edition 14 (11), 1229, 2003. doi.org/10.1163/156856203322553455
  14. Deb S, Abdulghani S and Behiri JC. Radiopacity in bone cements using an organo-bismuth compound. Biomaterials 23, 3387, 2002. doi.org/10.1016/S0142-9612(02)00039-X

• CHRC research grant.
• European Calcified Tissue Society/ Servier Award.
• Marie Curie Inter-European Fellowship (MEIF-CT-2003-502109).
• Doctoral studentship- University of London/Johnson & Johnson

ORCID
Scopus Author ID: 16314729600
Ciência ID: E319-65B5-8402
Loop profile: 1192448
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