Teses e Dissertações

TESES DE DOUTORAMENTO

Medicina

• ALMEIDA, Ana - Screening for retinopathy of prematury: how can we do better?
• BRANCO, Patrícia - Peritoneal histomorphology, biomarkers and clinical outcomes in patients with chronic kidney disease on peritoneal dialysis
• BRITO, Maria - Cervical squamous cell carcinoma (SCC) and cervical intraepithelial lesions (SILS) in hiv women: contribution of the local immune response (embargo 2 anos - 20.10.2023 a 20.10.2025)
• COUTO, Nuno - Tumoral exosomes profile in metastatic pancreatic adenocarcinoma patients during chemotherapy treatment
• FERNANDES, João - Social cognition in patients with schizophrenia and autism spectrum disorder
• FERREIRA, Alexandre - Improving the quality of colonoscopy 
• GOUVEIA, Catarina - Osteoarticular infections in pediatric patients : changes in epidemiology and treatment (embargo 2 anos - 22.06.2023 a 22.06.2025)
• LUZ, José - BestFLR. Randomized controlled clinical trial comparing preoperative portal embolization with polyvinyl alcohol particles (PVA) and coils versus N-butyl cyanoacrylate (NBCA)
• MARIA, Ana - Accounting for doctors and patients perceptions in telehealth services implementation
• PARREIRA, Leonor - A novel simplified approach to radiofrequency catheter ablation of idiopathic ventricular outflow tract premature ventricular contractions: from substrate analysis to results
• RAPOSO, Luís - Intracoronary transfer of human Umbilical Cord matrix‐derived Mesenchymal Stem Cells for the preservation of left ventricular function after acute myocardial infarction: assessment of invasive hemodynamic effects and potential underlying mechanisms in a large animal pre-clinical model (embargo 1 ano - 02.06.2023 a 02.06.2024)
• REIS, Teresa - Prescription of benzodiazepines by primary health care doctors: characteristics of prescribing trend and implementation of an online program (embargo 2 anos - 24.02.2023 a 24.02.2025)
• TELES, Rui - Transcatheter aortic valve implantation (TAVI) a reference model in percutaneous cardiovascular intervention

Biomedicina

• BOTA, Catarina - Testing the role of asymmetric migratory behaviors found in a novel population of mesendodermal cells (embargo 2 anos - 30.10.2023 a 30.10.2025)
• BURRINHA, Tatiana - Lysosome dysfunction, the link between aging and alzheimer’s disease? (embargo 3 anos - 27.01.2023 a 27.01.2026)
• COTOVIO, Gonçalo - Interhemispheric imbalance in mood disorders (embargo 3 anos - 24.01.2023 a 24.01.2026)
• CORREIA, Maria - Hydroxytyrosol and hypertension associated with chronic intermittent hypoxia: impact and contribution of AhR alternative pathway (embargo)
• DELGADO, Raquel - Regulation of survival and death pathways in chronic lymphocytic leukemia (embargo 3 anos - 28.06.2023 a 28.06.2026)
• FIALHO, Isabel - A psicoterapia de grupo de orientação grupanalítica : levantamento e caraterização a nível nacional, em meio hospitalar, e avaliação da eficácia em grupos psicoterapêuticos de diferentes dimensões
• MADEIRA, Natália - Rethinking memory acquisition: the rules of Memory cooperation and competition (3 anos embargo - 31.05.2023 a 31.05.2026)
• SOUSA, Daniela - Human Papillomaviruses in Head and Neck Squamous cell carcinomas: the relevance of HPV16 variants

Ciências da Saúde - especialidade Biomedicina

• BRANDÃO, Duarte - A cell-type specific selection system for stem cell therapy (and other) purposes (embargo 3 anos - 30.05.2023 a 30.05.2026)
• FERREIRA, Andreia - Modulating membrane traffic regulators to impair breast cancer progression (3 anos embargo - 13.03.2023 a 13.03.2026)

Mecanismos da Doença e Medicina Regenerativa (ProRegeM)

• CASTANHEIRA, Pedro - The role of rab11a and rab11b in breast cancer progression (embargo 3 anos - 20.04.2023 a 20.04.2026)
• LOPES, João - The role of Cerl2 in cardiomyocyte differentiation and heart regeneration (embargo 2 anos - 11.04.2023 a 11.04.2025)
• MEYER, Catarina - The mechanism of LAMP2A-mediated exosome biogenesis and their role in intercellular communication
• MIRFAKHAR, Farzaneh - Investigating the association of endocytic trafficking regulator CD2AP gene variant K633R and the risk of developing Alzheimer's disease (embargo 3 anos - 01.02.2023 a 01.02.2026)
• PESTANA, Sara - Testing the role of extracellular vesicles in early left right patterning

Envelhecimento e Doenças Crónicas

• KUBASOVA, Nadiya - Epigenetics and genetics of hematopoietic stem cells heterogeneity
• NETO, Matilde - Molecular mechanisms of melanin internalization and processing in keratinocytes (embargo de 3 anos - 29.06.2023 a 29.06.2026)
• RODRIGUES, Joana - Dissecting the role of ral gtpase in neuronal and glial structure and function
• SILVA, Daniela - The role of toll-like receptors expressing t cells in autoimmunity (embargo de 3 anos - 05.04.2023 a 05.04.2026)

DISSERTAÇÕES DE MESTRADO

Bioquímica para a Saúde

• BARRADAS, Bárbara - Protein Glycosylation in Cancer Drug Resistance (embargo de 3 anos - 15.03.2023 a 15.03.2026)
• CAÇÃO, Marta - Evaluating the protective effect of beries-derived poliphenol metabolites in mouse retina degeneration (embargo de 3 anos - 27.03.2023 a 27.03.2026)
• CHANDE, Andreia - Alternative splicing variants in breast cancer
• CRISPIM, Daniel - The role of the cytochrome P450-enzyme complex protein factors and other oxidoreductases in the mechanisnms of acquired cancer drug resistance (embargo 2 anos)
• FRANCISCO, Mafalda - Phenylalanine hydroxylase (pah) enzymosomes: development of a nanosystem for enzyme substitution/replacement therapies (embargo de 2 anos - 04.04.2023 a 04.04.2025)
• PEDRO, Margarida - Development of a screening pipeline to identify modulators of NRF2 activity (3 anos embargo)
• RAMOS, Carolina - The role of extracellular vesicles in chemotherapy resistance mediated by the breast cancer-liver axis (embargo 2 anos)
• SALVADO, Beatriz - Beating primary ciliary dyskinesia (embargo 2 anos)
• SESIFREDO, Isabel - Role of lysosome exocytosis in breast cancer progression (embargo 3 anos)

Gestão da Investigação Clínica

• AFONSO, Catarina - Coordenação de ensaios clínicos no Hospital da Luz Learning Health : relatório de estágio curricular
• COSTA, Carlota - Gestão do centro de investigação : promoção e organização de investigação interna
• EÇA, Rita - Digitalização de um centro de investigação clínica : desenho de um plano estratégico trabalho de projeto / Rita Horta Osório da Cunha de Eça 
• PICADO, Mariana - A fadiga em doentes com cancro do pulmão sob imunoterapia FADIMUN: estudo observacional prospetivo (1 ano embargo)

Investigação Biomédica (NBR)

• ALVES, Beatriz - VIP neuroepithelial circuit in immunity and metabolism (embargo 3 anos)
• COELHO, Pedro - Self-paced VS cued movement initiation : characterising behaviour and underlying neural circuits (embargo)
• DAMIÃO, Catarina - Exploring neuron-glia interaction in Drosophila and human¬derived neuropsheroids (embargo)
• FERRAZ, Luís - Exosomes in transcellular proteostasis and Age-Related Macular Degeneration
• FERREIRA, Bárbara - The role of glucagon : GCGR axis in pancreatic neuroendocrine
• GRENHAS, Maria - Comparative analysis of size-exclusion chromatography and ultracentrifugation for efficient isolation of extracellular vesicles in Multiple Myeloma (embargo)
• JUSTO, Inês - Exploring the role of the ESCRT-111 proteins in response to telomeric replication stress in ALT cancer cells (embargo)
• LAGOA, Filipa - The role of the immune system in MuSC aging during regeneration (embargo)
• LEÃO, José - Modulation of adenosinergic system as a therapeutic target for dysmetabolism  
• OLIVEIRA, Inês - Screening innate immunotherapy strategies in zebrafish xenograft models
• PACHECO, Maria - Developing 3D in vitro models of basal cell carcinoma (embargo)
• PEREIRA, Pedro - Extracellular vesicles: communication agents in prediabetes (embargo 1 ano)
• PINHO, Mariana - Dissection of glial contributions to neuronal structure and function in Drosophila melanogaster? (embargo 3 anos)
• QUADRADO, Carolina - Nutrient postingestive signalling: the asymmetry of the response of dopaminergic neuronal circuits (embargo 3 anos - 09.03.2023 a 09.03.2026)
• REIS, Fábio - Epithelial to mesenchymal transition pathway in pituitary endocrine tumours
• ROSADO, Pedro - Study of the impact of the IL-7R on non-small cell lung cancer (embargo)
• SALDANHA, Inês - Extracellular Vesicles as biomarkers of hepatic metastasis in pancreatic cancer patients (embargo)

Nutrição Humana e Metabolismo

• BAETA, Inês - Catering for athletes: food and nutritional considerations at international athletics championships (embargo 3 anos - 08.11.2023 a 08.11.2026)
• CALAFATE, Catarina - Evaluation of mental health, cognitive function and quality of life of breast cancer patients and the link with gut microbiota : a preliminary study
• CAMPOS, Teresa - The link between breast cancer treatment toxicity and gut microbiota: a preliminary study (embargo 3 anos - 17.07.2023 a 17.07.2026)
• CAPITÃO, Carolina - The relationship between tumor metabolic activity and body composition changes in patients with cancer (3 anos embargo)
• CARREIRA, Eduarda - The effects of a Mediterranean-style diet in heart disease patients running a cardiac rehabilitation program (embargo 3 anos - 29.11.2023 a 29.11.2026)
• FIGUEIRA, Carina - Effects of a weight loss program on cardiovascular risk in adults with obesity: the WLM3P study 
• FONSECA, Gisela - Efeito metabólico de um pequeno-almoço rápido e nutricionalmente equilibrado, desenvolvido para colmatar as necessidades da geração Y : estudo clínico aleatorizado e cruzado (1 ano embargo)
• FREITAS, Mariana - O efeito de uma dieta anti-inflamatória na atividade da doença e na qualidade de vida de pacientes com artrite reumatóide: ensaio clínico randomizado controlado paralelo (embargo 1 ano)
• GAMA, Maria - Impact on diet quality and dietary burden of sapropterin dihydrochloride use in children with phenylketonuria : a 6 months follow-up report (embargo)
• HASSAN, Mihabd - Role of the level of micronutrients (iron, zinc and vitamin D) in developing febrile convulsion in children under six years old (embargo 3 anos)
• HENRIQUES, Beatriz - Impacto da ingestão de uma infusão de funcho pelas mães na cólica infantil em bebés amamentados com leite materno (embargo 2 anos)
• LEMOS, Maria - Urinary biomarkers of biofortified beef in healthy women explored by untargeted metabolomics
• MONTEIRO, Ana - Multiple element exposure in a population of school-aged portuguese children : from health outcomes to preventive tools (embargo 2 anos)
• OLIVEIRA, Sofia - Assessment of exposure to plastic aditives flame retardants in portuguese pregnant women: the role of dietary consumption and associated health effects (embargo 30.11.2023 a 30.11.2025)
• PERES, Maria - Biochemical and anthropometric outcomes of patients with paediatric heterozygous familial hypercholesterolemia after COVID-19 pandemic lockdowns (embargo 3 anos)
• PISCO, Alexandra - Effects of a weight loss program on body composition in adults with obesiy: the WLM3P study
• RELVA, Bárbara - Caracterização das alterações metabólicas que ocorrem durante uma dieta hipocalórica de 8 semanas e a sua relação com a eficiência da perda de peso
• RIBEIRO, Laila - Avaliação da exposição in utero a contaminantes ambientais em recém-nascidos prematuros (embargo 1 ano - 09.01.2023 a 09.01.2024)
• RODRIGUES, Diana - Microspa – gut microbiota and axial spondyloarthritis: the impact on anti-tnf therapy
• SILVA, Rita - BIOMEQUIZ: validation of a food questionnaire to select stool donors (embargo 3 anos - 13.07.2023 a 13.07.2026)
• SOUSA, Catarina - Avaliação da exposição gestacional a metais pesados e a sua associação com o estado de saúde da mulher grávida & outcomes à nascença (embargo 2 anos - 22.09.2023 a 22.09.2025)
• VEIGA, Sofia - Levels of essential and toxic metals in adults with obesity undergoing a weight loss intervention: is there a link with meta-inflammation? (embargo 1 ano - 21.07.2023 a 21.07.2024)
• VIDINHA, Duarte - The effects of a school-based intervention on the dietary quality of mid-morning snacks in second grade Azorean children (embargo 1 ano - 24.07.2023 a 24.07.2024)

Saúde Mental nos Cuidados Primários

• DUTRA, Filipa - Parenting styles in victims of bullying in childhood and adolescence
• RAMOS, Laura - PTSD occurrence and management strategies during the COVID-19 pandemic

TESES DE DOUTORAMENTO

Medicina, Investigação Clínica

• ALMEIDA, Ana - Screening for retinopathy of prematury: how can we do better?
• BALSINHA, Maria - Users and health professionals' perspectives regarding Portuguese primary care services: a focus on dementia
• COELHO, Ana - Renal recovery after an episode of acute kidney injury
• FERREIRA, Ana - Bone-derived hormones, bone disorders and cardiovascular disease in kidney transplanted patients
• FERREIRA, Bruna - The role of extracellular vesiclesin multiple myeloma
• MARTO, Natália - In vivo phenotyping of sultia enzymes in man implications for precision medicine
• NEVES, Marisa - The role of high-density lipoproteins in the activation of T lymphocytes and regulation of immune response
• OURÔ, Susana - Biological and surgical determinants in the treatment of rectal cancer 
• ROSA, Sílvia - Microcirculation dysfunction in hypertrophic cardiomyopathy
• SOUSA, Marcelo - Substantia Nigra in Parkinson’s disease: exploring the encoding of movement kinematics by Dopaminergic Neurons
• SILVA, Tiago - Circulating micro-rna profiles according to atherosclerotic disease expression : a contribute to phenotype characterization and insights into pathophysiology

Biomedicina

• BORBINHA, Jorge - The effects of metabolic reprogramming during zebrafish tissue regeneration (embargo 3 anos - 07.12.2022 a 07.12.2025)
• LOPES, Liliana - Molecular mechanisms of melanin secretion by melanocytes and processing within keratinocytes (embargo 3 anos - 21.12.2022 a 21.12.2025)

Ciências da Saúde, Biomedicina

• MATIAS, Ana - Dissecting the differential molecular signature in patients From african-origin with triple-negative breast cancer

Mecanismos de Doença e Medicina Regenerativa (ProRegeM)

• MARQUES, Graça - Characterization of novel factors regulating neural stem cell proliferation, temporal fate and neuronal diversity (embargo 3 anos - 29.04.2022 a 29.04.2025)
• MONTEIRO, Ana - Underlying role of glycation in the pathogenesis of Parkinson’s disease (embargo 3 anos - 30.11.2022 a 30.11.2025)
• PINA, Ana F. - Non-communicable diseases stratification and integration: a clinical approach (embargo 3 anos - 13.09.2022 a 13.09.2025)
• RODRIGUES, Cátia - Neuronal and glial growth and development: dissecting the role of RalA and exocyst in  Drosophila peripheral nervous system

Saúde Pública Global

• MARQUES, Maria - Factors influencing the quality of relationship in dementia: a mixed-methods approach (embargo 3 anos - 07.11.2022 a 07.11.2025)

DISSERTAÇÕES DE MESTRADO

Bioquímica para a Saúde

• BARATA, Isabel - The Role of Progesterone Receptor Membrane Component 1 (PGRMC1) in Cytochromes P450 (CYP)- Mediated Drug Metabolism and its Implication in Chemotherapy Resistance
• BENTO, Luís - Anti-inflammatory activity of berries driven polyphenols in zebrafish larvae fed with oxidizedlipids and LPS
• COSTA, Ana - Suscetibilidade genética em doentes COVID19 hospitalizados: o caso português
• DOMINGUES, Ana - Role of micrornas in cancer drug resistance
• DUARTE, Catarina - Role of microRNAs and epigenetics modifications in paclitaxel resistance in a breast cancer cell line model
• VALE, Ana - Biological relevance of VUS identified in ATM gene and the role in DNA damage response

Gestão da Investigação Clínica

• ABREU, Daniela - Coordenação de estudos clínicos no Centro Hospitalar de Lisboa Ocidental
• BARBOSA, Ana - Relatório de estágio em coordenação de investigação clínica na Blueclinical, ltd
• BASTOS, Inês - Ensaios clínicos da iniciativa do investigador e descrição do estágio em coordenação de estudos clínicos no IPO Porto
• CAETANO, Madalena - Relatório de estágio curricular em coordenação de estudos clínicos no Centro Hospitalar de Lisboa Ocidental, E.P.E.
• COELHO, Carolina - Relatório de estágio em coordenação de ensaios clínicos de oncologia
• CORREIA, Miguel - Estágio em coordenação de estudos clínicos na CUF Academic Center
• COSTA, Mariana - Estágio de coordenação de estudos & atividades de monitorização e start-up de ensaios clínicos na AIDFM-Associação para a Investigação e Desenvolvimento da Faculdade de Medicina 
• FIALHO, Helena - Estágio de monitorização de estudos na keypoint, group evidenze
• GOEDE, Kay Shawnee - Estágio em gestão e monitorização de estudos clínicos na Novartis Farma
• INÁCIO, Ana - Coordenação de estudos clínicos no centro hospitalar lisboa ocidental, E.P.E.
• LEMOS, Beatriz - Start-up, monitorização e coordenação de estudos 
• PINTO, Catarina - Relatório de estágio curricular em coordenação de estudos clínicos no Lusíadas Knowledge Center
• MEDEIROS, João - Relatório de estágio de coordenação em investigação clínica em dois hospitais parceiros da Blueclinical CRP
• NETO, Pedro - Relatório de estágio em tarefas regulamentares e de monitorização na W4Research
• OLIVEIRA, Madalena - Coordenação de estudos clínicos na Blueclinical
• RIBEIRO, Miguel - Relatório de estágio curricular em coordenação de estudos clínicos no Centro Hospitalar Universitário Cova da Beira
• SILVÉRIO, Catarina - Start-up e monitorização de estudos clínicos

Investigação Biomédica

• ALMEIDA, Vicente - Regulation of γδ17 T cell homeostasis by stress-derived signals (embargo 3 anos - 17.11.2022 a 17.11.2025)
• AMORIM, Filipa - Ovarian cancer zebrafish avatar for personalized therapy (embargo 3 anos - 16.11.2022 a 16.11.2025)
• AMORIM, Joana - Polymeric nanoparticles for local delivery of multicolor genetic circuits in breast cancer (embargo 3 anos - 02.12.2022 a 02.12.2025)
• ANTÓNIO, Patrícia - The effect of sphingosine-1-phosphate in lymphocytes of patients with pancreatic cancer (embargo 2 anos - 14.12.2022 a 14.12.2024)
• CAPUCHO, Adriana - The role of carotid body in brain insulin resistance and neurodegeneration
• CASTAÑEDA MATIZ, Luisamaria - Unveiling the role of DIPK2B in hematopoietic development and primary immunodeficiencies (embargo 3 anos - 23.11.2022 a 23.11.2025)
• CATARINO, Joana - Probing striatal subpopulations in outcome-dependent action control in rats
• COELHO, Rita - Characterization of cellular organelles and the endo-lysosomal pathway in choroideremia patient cells (embargo 3 anos - 22.11.2022 a 22.11.2025)
• COSTA, Miguel - Biological effect of Type I procollagen carboxyterminal propeptide in breast cancer tumor microenvironment
• CUNHA, César - Disclosing lysosomal dysfunction with neuronal aging : a potential mechanism of early synaptic degeneration in alzheimer's (embargo 3 anos - 22.03.2022 a 22.03.2025)
• DIAS, Maria - Mechanisms of reinnervation during wound healing: novel roles for epithelial-glial communication (embargo 3 anos - 04.05.2022 a 04.05.2025)
• KAMIKI, Jéssica - Mucosal-associated invariante T cells : novel players in pancreatic cancer
• LOPES, Francisco - Investigating the role of innate immune memory in microglial-mediated synaptic remodeling (embargo 3 anos - 11.05.2022 a 11.05.2025)
• MARQUES, Ana - Contribution of high histone acetylation in memory allocation (embargo 3 anos - 26.04.2022 a 26.04.2025)
• MOTA, Sara - A new paradigm to study NF-κB in vivo and the role of dietary phenolic metabolites using drosophila (embargo 3 anos - 10.05.2022 a 10.05.2025)
• PACHECO, Rita - Proteomic approach to the caracterization of unknown origin male infertility
• PEREIRA, Tiago - Uncovering the mechanism of CD2AP behind Alzheimer’s disease (embargo 3 anos - 23.11.2022 a 23.11.2025)
• PIRES, Dinis - GLP1 acts on the carotid body to modulate glucose homeostasis and cardiorespiratory responses (embargo 3 anos - 15.12.2022 a 15.12.2025)
• SAAB, Maria - Engineered cardiac tissues with improved maturation for regenerative medicine (embargo 2 anos - 30.11.2022 a 30.11.2024)
• TEIXEIRA, Melissa - Nanoformulations of novel metal-complexes as potential antitumor agents

Nutrição Humana e Metabolismo

• CASTELA, Inês - Unravelling the role of adipose tissue metabolism in diet-induced weight loss : results from a randomised controlled trial
• LICKFOLD, Mafalda - Associação entre alterações da composição corporal e o perfil cardiometabólico após cirurgia metabólica e bariátrica
• PITA, Débora - Portuguese questionnaires for assesing dietary supplements usage by athletes
• PROJECTO, Maria - The influence of anthocyanin treatment on the mesenteric adipose tissue expression of enampt in animal models of obesity
• REMÍGIO, Inês - Associação entre o estado nutricional de indivíduos que tiveram diagnóstico de covid-19 e sintomas persistentes da doença
• RODRIGUES, Tânia - The efficacy of faecal microbiota transplantation for the treatment of irritable bowel syndrome: a sistematic review and meta-analysis
• SANTOS, Gilberto - Fecal samples with more bifidobacteria protect against intestinal permeability

Saúde Mental nos Cuidados Primários

• MAHDY, Marwa - Assessment of Saudi public knowledge and attitudes toward mental health disorders and its demographic correlation (embargo 3 anos - 18.05.2022 a 18.05.2025)