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José Manuel Inácio

Investigador  Investigador Doutorado
Post-Doctoral Researcher
Ph.D. in Molecular Biology from ITQB-UNL. At NMS, my immediate interest is to understand the genetic and molecular control of heart development and disease using Stem Cells, generating iPSCs from patients and gene-editing variants.
- Inácio JM, JvG Lopes, AM Silva, F Cristo, S Marques, ME Futschik, and JA Belo. (2021). DAND5 inactivation promotes cardiac differentiation in mouse embryonic stem cells. Front Cell Dev Biol. 2021 Apr 13;9:629430. - Inácio JM, Almeida M, Cristo F, Belo JA. (2020). Generation of a gene-corrected human induced pluripotent stem cell line derived from a patient with laterality defects and congenital heart anomalies with a c.455G > A alteration in DAND5. Stem Cell Res. 42:101677. - Bover O, Justo T, Pereira PNG, Facucho-Oliveira J, Inácio JM, Ramalho JS, Domian IJ, Belo JA. (2018). Loss of Ccbe1 affects cardiac-specification and cardiomyocyte differentiation in mouse embryonic stem cells. PLoS One. 13: e0205108 - Bonet F, Pereira PNG, Bover O, Marques S, Inácio JM, Belo JA. (2018). CCBE1 is required for coronary vessel development and proper coronary artery stem formation in the mouse heart. Dev Dyn. 247: 1135-1145. - Belo, JA, Marques, S., and J.M. Inácio (2017) The Role of Cerl2 in the Establishment of Left-Right Asymmetries during Axis Formation and Heart Development. J. Cardiovasc. Dev. Dis. 4, 23. - Inácio JM*, Cristo, F.*, Rosas, G., Carreira, I.M., Melo, J.B., Almeida, L.P., Mendes, P., Martins, D. S., Maio, J., Anjos, A., and JA. Belo (2017). Generation of human iPSC line from a patient with laterality defects and associated congenital heart anomalies carrying a DAND5 missense alteration. Stem Cell Research 25: 152–156. *equal authors.