I am a biochemist with over half a decade dedicated to the study of cell and whole-body metabolism, spanning from metabolomics to isotope tracing experiments, both in vitro and in vivo, using background in analytical chemistry techniques (HRMS; NMR).
My interest in metabolic disorders started when one of my family members was diagnosed with type 2 diabetes. Watching them completely, changing their life habits and witnessing the impact of those changes in their health, completely fascinate me into study Metabolism During my undergraduate studies I worked on the prognostic value and protective role of paroxanase 1 in obesity comorbidities models. After that, I moved to the University of Coimbra to pursue my Master studies and do my thesis work investigating the therapeutic target of Pentose Phosphate Pathway (PPP) in hepatocellular carcinoma models, using stable isotope tracing and NMR. Still moved by the desire to understand more and more about metabolism, I joined the Metabolomics Core at Children’s Research Institute at University of Texas Southwestern Medical Centre, in Dallas Texas, to determine relative and quantitative concentration of metabolites present in biological samples. In this position, I’ve collaborated with a variety of different internal and external labs and some of the top scientists in the world. More recently, I join the Metabolic Reprogramming in Hereditary Diseases Lab at Faculdade de Ciências Médicas|NOVA Medical School (FCM|NMS) to study mitochondrial, and more particularly Krebs Cycles dysfunction that lead to metabolic reprogramming in cases of inborn errors of Metabolism and Immunity.