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Ed. Cinzento piso 2 gabinete 2.17

Cláudia Guimas Almeida

Investigador  Investigador Principal
Principal Investigator

Principal investigator (FCT CEEC; 2019-2025). PhD Neurosciences (USA). Post-doc Cell biology (France). Co-coordinator NBR master program. Scientific Coordinator Microscopy facility. iNOVA4Health representative in the NMS Scientific Council.

  • Perdigão C, Barata MA, Burrinha T, Guimas Almeida C*. Alzheimer's disease BIN1 coding variants increase intracellular Aβ levels by interfering with BACE1 recycling. J Biol Chem. 2021 297(3):101056. doi: 10.1016/j.jbc.2021.101056.
  • Burrinha T, Martinsson I, Gomes R, Terrasso AP, Gouras GK, Almeida CG*. Up-regulation of APP endocytosis by neuronal aging drives amyloid dependent-synapse loss. J Cell Sci. 2021 Apr 28:jcs.255752. doi: 10.1242/jcs.255752. Epub ahead of print. PMID: 33910234.
  • Perdigão C, Barata MA, Araújo MN, Mirfakhar F, Castanheira J, Guimas Almeida C*. "Intracellular trafficking mechanisms of synaptic dysfunction in Alzheimer's disease". Front Cell Neurosci. 2020 Apr 17;14:72. doi: 10.3389/fncel.2020.00072. eCollection 2020. Review.
  • Guimas Almeida C*, Sadat Mirfakhar F, Perdigão C, Burrinha T. Impact of late-onset Alzheimer's genetic risk factors on beta-amyloid endocytic production. Cell Mol Life Sci. 2018 Jul;75(14):2577-2589. doi: 10.1007/s00018-018-2825-9. Epub 2018 Apr 27. Review.
  • Ubelmann F, Burrinha T, Gomes R, Salavessa L, Ferreira C, Moreno N., Almeida CG*. Bin1 and CD2AP polarize beta-amyloid endocytic generation. EMBO Rep. 2017 Jan; 18(1):102-122. doi: 10.15252/embr.201642738.
  • 2019-2025 Scientific Stimulus Contract (CEEC 2017), Foundation for Science and Technology (FCT), Portugal
  • 2013-2018 “Investigador FCT”, Foundation for Science and Technology (FCT), Portugal 2017 Award Maratona da Saúde "Impact of the genetic risk factor CD2AP on the development of Alzheimer's disease
  • 2015 NOVA/Santander-Totta award for collaborative project in life sciences, Portugal
  • 2007-2009 European Molecular Biology Organization, EMBO long-term fellowship, Paris, France
  • 2007-2009 European Molecular Biology Organization, EMBO long-term fellowship, Paris, France