Esteves F, Rueff J, Kranendonk M. The Central Role of Cytochrome P450 in Xenobiotic Metabolism-A Brief Review on a Fascinating Enzyme Family.
Journal of Xenobiotics (2021) 11, 94-114. DOI: 10.3390/jox11030007
Fernandez-Checa JC, Bagnaninchi P, Ye H, Sancho-Bru P, Falcon-Perez JM, Royo F, Garcia-Ruiz C, Konu O, Miranda J, Lunov O, Dejneka A, Elfick A, McDonald A, Sullivan GJ, Aithal GP, Lucena MI, Andrade RJ, Fromenty B, Kranendonk M, Cubero FJ, Nelson LJ. Advanced preclinical models for evaluation of drug-induced liver injury - consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET].
Journal of Hepatology (2021), 24, S0168-8278(21)00441-4 DOI: 10.1016/j.jhep.2021.06.021
Esteves F, Urban P, Rueff J, Truan G, Kranendonk M.
Interaction Modes of Microsomal Cytochrome P450s with Its Reductase and the Role of Substrate Binding. International Journal Molecular Science (2020) 21(18): 6669 DOI: 10.3390/ijms21186669
Esteves F, Campelo D, Gomes BC, Urban P, Bozonnet S, Lautier T, Rueff J, Truan G, Kranendonk M. The Role of the FMN-Domain of Human Cytochrome P450 Oxidoreductase in Its Promiscuous Interactions with Structurally Diverse Redox Partners. Frontiers in Pharmacology (2020) 11:299. eCollection 2020. DOI: 10.3389/fphar.2020.00299
Campelo D, Esteves F, Brito Palma B, Costa Gomes B, Rueff J, Lautier T, Urban P, Truan G, Kranendonk M. Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450. International Journal of Molecular Sciences, (2018) 19: pii: E3914. DOI: 10.3390/ijms19123914
Amit Pandey, Colin James Henderson, Yuji Ishii, Michel Kranendonk, Wayne Backes and Ulrich Zanger Editorial: Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function Frontiers in Pharmacology (2017), 8:881 DOI: 10.3389/fphar.2017.00881
Diana Campelo, Thomas Lautier, Philippe Urban, Francisco Esteves, Sophie Bozonnet, Gilles Truan and Michel Kranendonk. The hinge segment of human NADPH-cytochrome P450 reductase in conformational switching: the critical role of ionic strength. Frontiers in Pharmacology (2017) 8:755 DOI: 10.3389/fphar.2017.00755
McCammon KM, Panda SP, Xia C, Kim JJ, Moutinho D, Kranendonk M, Auchus RJ,
Lafer EM, Ghosh D, Martasek P, Kar R, Masters BS, Roman LJ. Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype. Journal of Biological Chemistry (2016), 291:20487-502. DOI: 10.1074/jbc.M116.716019