Centre For Toxicogenomics And Human Health (ToxOmics)

ToxOmics aims for interdisciplinary I&D activities using genomic and post-genomic   methodologies to study the molecular, biochemical and cellular effects of human genetic diseases  and harmful environmental effects, through interrelated approaches 

  1. exposure evaluation, biological responses and genome harmful agents and biological monitoring
  2. genic expression variability and regulation of disease and therapeutic response
  3. evaluation and development of toxicogenomic and toxicoproteomic biomarkers.

Our mission revolves around prevention,susceptibility to disease and advanced training in toxicogenomics and human health.

ToxOmics has INSA as a partner, where 5 research groups are based, namely: Genetic Diseases, Functional and Structural Genomics, Environmental Genotoxicity, DNA Analysis Technologies, Signal Transduction Pathologies and Associated Pathologies.

ToxOmics contibutes to the following Sustainable Development Goals (SDG) from UN:

ODS3   ODS4

Know more about the dedication of ToxOmics and NOVA Medical School at our Sustainability page.

COORDINATOR

Michel Kranendonk, PhD 

Investigation groups

Integrative Biomedicine

Alisson M. Gontijo

Tumor Morphology And Microenvironment

Ana Félix

Cytoskeleton in Development and Disease

Ana Pimenta Marques

EpiDoC Unit – Musculoskeletal Diseases, Ageing, and Digital Health

Ana Rodrigues Nuno Mendonça

Person-Centered Research

Bruno Heleno

Proliferation and Fate Regulation of Stem Cells

Catarina Homem

Neurogenetics of Locomotion

César Mendes

Neuroscience of Aging and Alzheimer

Cláudia Guimas Almeida

Metabolism and Nutrition

Conceição Calhau Ana Faria

Membrane Traffic in Disease

Duarte Barral

Gene Therapy

Gabriela Araújo Silva

Translational Tumor Immunology

Guadalupe Cabral

Human Immunobiology and Pathogenesis

Helena Soares

DysBrainD - Dysmetabolism in Brain Diseases laboratory

Hugo Vicente Miranda

Cancer Metabolism and Microenvironment

Jacinta Serpa

Nanomedicine & Clinical Oncology

João Conde Isabel Fernandes

Genetic Kidney Diseases

Joaquim Calado

Stem Cells and Development

José António Belo

Immune Response and Vascular Disease

José Delgado Alves

Metabolic Diseases Research (MEDIR)

Maria Paula Macedo

Xenobiotic Metabolism

Michel Kranendonk

Molecular Mechanisms of Disease

Miguel Seabra

Mental Health

Miguel Xavier Manuel Gonçalves Pereira

Disease Transcriptomics

Nuno Barbosa Morais

Integrated Pathophysiological mechanisms

Nuno Neuparth

Lysosomes and Disease

Otília Vieira

Metabolic Reprogramming in Mitochondrial Disease

Paulo Gameiro

Proteostasis and Intercellular Communication

Paulo Pereira João Vasco Ferreira

Immune Dysregulation, Infection, and Antibiotics Resistance

Pedro Póvoa

Inflammation and Neurodegeneration

Raffaella Gozzelino

Neuronal Growth and Plasticity

Rita Teodoro

Computational and experimental biology

Rune Matthiesen

Degeneration and Ageing

Sandra Tenreiro

ReGen – Resistance & Genome integrity

Sebastião Rodrigues Susana Nunes Silva

Computational Cardiology, AI and Data Science for Health

Sérgio Laranjo

Neuronal Control of Metabolic Disturbances: Therapeutic Strategies

Sílvia Vilares Conde

Renal, Cardiovascular and Metabolic Pharmacology

Sofia Pereira